Well, I think my kids will agree that its definitely in the top 5000 things that are indirectly present in our lives. To me, it's a sign of an unserious society - making trivial matters important while important matters are trivialized. Thinking one can choose a unique gender/pronoun for themselves is the height of narcissism - and I just cannot take anyone who does that seriously.
So far as sports and gender, i am fine with people behaving and dressing any way they want as long as they are not hurting others. Wear a tutu, have the offending part shrunken, removed, reformed into a fake labia or cut it off and have a French chef serve it up at a party as one guy in Tokyo did. We all should be free to make whatever choices we want, but none of us has the right to demand society change everything so that we can feel good about every choice we make. And we don't have a right to discriminate against young women who want to compete in sports. We also don't have a right to invade women's showers and toilets because we claim to feel like a woman ourselves. Most of this is common sense, which I know is especially unfashionable in the West these days.