There I was just reading the news bulletins and ...

[TheBaldOne]

I have posted before saying that when you have become a domainer you will ALWAYS be a domainer. This evening the truth of that has been proved yet again.

A little while ago there I was just picking through a few science and medicine journals and saw a report, it stuck out like a big pink elephant in the room - possible replacement for antibiotics! Five minutes later there I was on GoDaddy checking out whether a domain had been registered, without any real hope it has to be said as normally in such situations 99.99% of the time the relevant domains are already of course gone.

This time though, obviously as I am posting this, the domains both singular and plural were not registered - of course they are now!

Now being a biochemist in the long and distant past gives me just a little edge over most domainers in the field, but, surely, the Dutch company who have developed a new method for treating antibiotic resistant bacteria would do more than just register the .com domain name for their 'brand' name for their specific treatment. Luckily for me they did not.

The company concerned has developed an enzyme treatment using the naturally occurring enzyme 'endolysin'. Now why is this so important, well just imagine MRSA's as a simple example. Treatment and prevention of MRSA's is a huge business worldwide. Now it may be possible that they (and other bacterial infections) will be treatable with a new kind of treatment. At present the treatment is restricted to a cream for skin treatment, though it is hoped that a tablet form to treat internal infection will be available within 5 years. So my guess is I spent a few odd dollars wisely this evening registering:

Endolysin.com

and

Endolysins.com

I am a very happy little 'retired domainer' this evening, another couple of domains added to my pension portfolio. As I say 'once a domainer, always a domainer'.

 

[ecalc]

I’m not a biochemist but I pass gas like a virtuoso …

Pros
1. Drug companies accumulate both chemical and brand domain names. Today might be your lucky day.

Cons
1. The overall success rate for drugs moving through clinical trials to FDA approval from late 2003 to 2011 is about one in 10. source
2. Regulatory approval does not guarantee drug sales.
3. Drug companies push brand names, not chemical names.
4. Mad scientists and bored domainers type in chemical drug domains then x out while Honey Boo Boo and Mama June click ppc ads nonstop on simpler names.
5. I just saw a pink elephant.

You can avoid clinical trial and market risks by hitching your wagon to a proven blockbuster drug. For example, big pharma Shire sells $1.8B of brand name Vyvanse per year. Proper name lisdexamfetamine dimesylate and believe it or not lisdexamfetaminedimesylate.com can be hand regged. Or let's not and say we did. Good luck!

 

[TheBaldOne]

@ecalc - A very good reply.

To answer a few points you raise.

Cons

1. The 'cream treatment' in question has already been developed by a drug company and passed through the clinical trial stages, and has already received clearance in both Germany and Holland as the first stage, obviously the company in question (or who ever buys it IMO) will likely now seek approval from authorities around the world.

2. Of course regulatory approval does not equate to drug sales, but then again I have not gone after the brand name. I went for the general name of the enzyme and enzyme type. Now that the method has been shown to work I am sure that other companies will follow through with development of their own and bring in new treatments of their own on the general framework. (I am sure that going after the brand name would be suicidal and would immediately end up with the name being taken under a UDRP claim.)

What a successful clinical trial and approval does do though is allow for the potential of huge sales.

3. True chemical companies do push brand names - but I am not concerned about that. The way I look at it is that although there are hundreds or even thousands of different kinds of cheeses, all with their own names, they remain grouped together under the family type of foodstuff called 'cheese', I have registered 'cheese' not 'Cheddar', 'Lancashire', 'Edam', 'Gorgonzola', etc.

'Endolysin', or rather 'endolysins' will likely be the name of the group of drugs and/or treatment, the field will undoubtedly be huge IMO, and 'if' it does succeed then the term will become more popular than 'penicillin' is.

4. True again, but then again I think that the treatment for 'acne' alone will likely produce enough general public interest in the coming years to more than the fact that this is actually the name of an enzyme or group of enzymes. Seems to me therefore that 'Honey Boo Boo' and 'Mama June' will be clicking ads pretty soon.

5. If you just saw a pink elephant then you had better check it out and see whether the domain is available. With discount codes, etc. you could invest less than $2 to get the domain that might, just 'might' mind you, be worth a heck of a lot more in a very short time. It will be a gamble for sure, but considering the potential returns it is worth the investment of just a couple of dollars IMO.

Finally, there is a big difference between registering the name of an enzyme or family of enzymes such as endolysin/s and registering 'lisdexamfetamine dimesylate', and if you don't see that then may I suggest you return to studying 'Domaining 101'. LOL

 

[TheBaldOne]

Through the day I have been watching the 'news' slowly start to mount around the world about the endolysin breakthrough. It seems that from a small conference in London this week it is now being recognised as a major breakthrough worldwide in the fight against MRSA, etc., which of course is a very good thing for me ( :P ). For any who are interested just do a Google news search for 'endolysin'.

I have expanded the initial two registrations by adding the following domains:

EndolysinTreatment
EndolysinTreatments
EndolysinTherapy
EndolysinTherapies

(all .com of course)

However, with all such successes they bring along their own set of problems. As it is at the moment no one will be willing to pay what the domains are worth (according to me of course). Now that leaves me with the dilemma of whether to develop the domains or not. So now I am having to consider looking for a 'proven' developer in the field of medicine and/or science who can utilize the domains and build appropriate sites on them with appropriate monetization.

The other option is leasing, which though on paper makes great commercial sense, I have yet to see any real successes with.

Headaches - I think it is soon going to be time for an aspirin (and I like everybody else refer to it as aspirin and not '2-acetoxybenzoic acid' - LOL).

.......................

Surprisingly this post was not appended to my post of earlier today as I expected it to be.

 

[DU]

News has been mounting for years now not days buy good luck anyway.

 

[TheBaldOne]

Grace, you are absolutely correct in a way. The Russians knew about and were using bacteriophages for decades, unfortunately the 'Cold War' meant that many of their research papers never got translated into English and therefore as a whole was greatly overlooked in the west. Though the USSR continued research mainly in Tbilisi in Georgia. Of course the west concentrated on antibiotics.

The real breakthrough though has come about because this is the first endolysin to get permission for use in the west on humans (some permissions had been previously granted for the use on bacteria in foodstuffs). But the 'news' I refer to is the fact that this is now being broadcast in the public press and not just in science and medical journals. This spread of knowledge will mean that people will start looking up endolysin treatments and demand them of their doctors - and guess where they will be looking for that information.

Now if there was ever a domain or group of domains whereby 'luck' should not be needed it is these. With the MRSA costs exceeding $14billion a year alone and with the treatment for such things as acne added on then it is likely that this one branch of enzymology can look forward to a thriving future measured in the tens of billions of dollars annually, especially when veterinary medicine and further food preservation is included as well as human medicine.

These domains are like being able to register penicillin.com at the time of its first mass production.

EDIT
Just read the following report in 'Nature Biotechnology News':

"Actavis snapped up Chicago-based Durata Therapeutics to gain a next-generation antibiotic to treat skin infections. On October 6 Actavis agreed to pay $675 million in cash and up to $146.5 million in milestones if Durata's new drug Dalvance (dalbavancin) meets regulatory and sales goals."

Somehow I think Actavis will be reappraising its 'valuation' IMO. LOL

But it does show just what the industry is worth.

 

[DU]

Maybe you will get traffic and convert it but most searches will yield the same news sources and companies that you did.
If you do ok it will be a nice story to tell though.

I would not get my hopes up for a big resale but you never known... it's gotta be worth more than $8 right?

Penicillin
Statin
Statins
acetaminophen

Are parked

Lisinopril
amlodipine
Azithromycin
Amoxicillin

Have mini site and owned by one guy - probably want to see if he's interested in growing his collection...

omeprazole
Owned by AZ - so some do buy their generic drug names I guess.

 

[ecalc]

... I have registered 'cheese'

Consider the possibility that lysin is cheese and you have registered endocheese.

… the treatment for 'acne' alone will likely produce enough general public interest in the coming years to more than the fact that this is actually the name of an enzyme or group of enzymes. Seems to me therefore that 'Honey Boo Boo' and 'Mama June' will be clicking ads pretty soon.

Honey and Mama may be fixin' to click but they and their archetypes will search “fix my zits” a million times before typing in or searching endolysin.

We all go overboard. My weakness is cocoa puffs.

 

[DU]

Honey and Mama may be fixin' to click but they and their archetypes will search “fix my zits” a million times before typing in or searching endolysin.

They been house hunting in Hampton, GA. I bet even there they've seen XOUT and ProActiv commercials.

We all go overboard. My weakness is cocoa puffs.

I have a weakness for High Gravity beer.

 

[TheBaldOne]

I was going to be sarcastic to the above replies, but thought better of it and therefore deleted my reply before posting it.

I think my reply should just say that I am extremely comfortable with these hand-reg'ed domains. I actually class them as perhaps being the most valuable domains I have EVER owned, and that is over more than a decade in the business. But perhaps that is because I know the following:

- the industry financials
- the areas of research
- the applications
- the marketing of the products
- the opportunities for monetization
- the longevity of the investment
- the longevity of the returns

As I said in the OP it most probably helps in this case that I have a biochemistry background.

But two comments I do feel I have to pass is that everyone refers to them as 'endolysins' and not 'lysins' (please also note the plural as the range is going to be tremendous), and there is a very good reason for that. Also all six domains together cost me in total less than $30, which is a lot less than $8 each.

I initially posted this thread as it showed that even today there are opportunities to hand reg a domain if you are lucky enough to read or hear of something and be the first to act upon it (well at least in my opinion it does) and, of course, my amazement at actually getting the domains. I happen to know that even 'the greats' in the industry do that on a daily basis and I wanted to show that literally every domainer has the same chance and that I had done it.

Now I wonder, was ebola.com really worth all that money?