The thing about hand regging future tech is the psychological effect of owning a part of the future. Whether it takes off or not, most likely there hasn't been a lot lost. It's generally done in good fun, with some possibility at the end. It's under ten bucks at most registrars. You can hand reg 100 names for well under a $1000 bucks. Not too many people are going to be drastically effected by some hand regging. If it's going to change your lifestyle, stay away. Otherwise enjoy it.
On the other hand, there are many stories of veterans paying $10,000, $100,000 and upwards on a domain only to be holding on to it for years with no significant inquiries.
Pick and choose your battles, and most importantly enjoy the journey.