Find a successfull duo called filehandling and sell it on .
If you struggle to find a duo with these names, quite posible, then I would most definatly say one of two things.
You could start a file upload service, quite a saturated market, which in my opinion is quite monopolistic competition based in it's structure with a lot of small companys running the show with room for new startups to grab some of that market share.
Or you could create a site that works similar to filehosting, the type in which links are sent to recipitents email addresses and the files are kept on the server for a matter of days before deletion. I know little about these services or how they operate but both are worth looking into.
Right now, I think the domain could fetch you a tidy little sum as they are good keywords but not nessecarily the type of keywords somebody looking to upload files would use in their searches.
I hope you aren't disgraced by the terrible joke at the start of my post and I hope this helped you a little.