I own more than 2K hand reg domains, but I have a reason, if you don't, then the best path is to "go grow potatoes" in a kind manner of saying, so if I was not knowing what to do without having a reason on my back, then I would be wasting my time and money.
Why, because in almost 5 years of domain investing I sold only 4 domains totaling 2500K USD but I spent more than 60K on hand regs, so in conclusion without a reason you feed the daddy Registrars, there is no profit only loses, the domains I sold are not related to my reason of domaining, that is why I tell you this.
But if you learn domaining and focus on quality over quantity you can make a profit, you would have to detect the domains which will sell for sure but not reg the ones which will be dropped for sure.
edit 1: specify domaining period.
edit 2: rephrased words to make logic.