I'm working on various statistical experiments to determine the optimal conditions for sending sales pitches.
In my first experiment, I pitched 100 companies (of all sizes) on a domain -- the first 40 on a Mon. afternoon, the second 40 on a Tue. afternoon, and the last 20 on a Wed. afternoon. I gave each of the 100 until Friday to provide me an initial response. The results:
* Pitched on Monday - 5 / 40 (12.5%) responded asking for price by Friday
* Pitched on Tuesday - 3 / 40 (7.5%) responded asking for price by Friday
* Pitched on Wednesday - 1 / 20 (5%) responded asking for price by Friday.
So it appears that the earlier in the week you e-mail them given they must respond by Friday, the better your chances. I'll need to perform further experiments to determine whether Monday's excellent results were due to the day of week pitched or the generous amount of response time allotted.
Please don't make any critical decisions base on these findings, as the sample size of companies I e-mailed in this trial was very small. But in the event you're torn between e-mail pitching a key prospect between Monday (logic: more time to consider your offer) versus later on the week (logic: expressing urgency, putting the clamp on), it looks like Monday's your better bet.