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Covid19-Coronavirus updates and news

Labeled as news in The Break Room, started by Mister Funsky, Feb 22, 2020

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  1. Mister Funsky

    Mister Funsky Top Contributor VIP

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    LOL...I just spent ten minutes searching for a bidet...think I found one that will work...not wanting to do the TP hunt this winter again.
     
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  2. Sutruk

    Sutruk Top Contributor VIP

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    FDA Approves First Treatment for COVID-19

    https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-covid-19

    Today, the U.S. Food and Drug Administration approved the antiviral drug Veklury (remdesivir) for use in adult and pediatric patients 12 years of age and older and weighing at least 40 kilograms (about 88 pounds) for the treatment of COVID-19 requiring hospitalization. Veklury should only be administered in a hospital or in a healthcare setting capable of providing acute care comparable to inpatient hospital care. Veklury is the first treatment for COVID-19 to receive FDA approval.
     
    Last edited: Oct 23, 2020
  3. koolishman

    koolishman Upgraded Member Blue Account

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    Surprising, since WHO study says otherwise
     
  4. Sutruk

    Sutruk Top Contributor VIP

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    Yes I saw the WHO study... on the FDA trials they say remdesivir improved the recovery time:

    "One randomized, double-blind, placebo-controlled clinical trial (ACTT-1), conducted by the National Institute of Allergy and Infectious Diseases, evaluated how long it took for subjects to recover from COVID-19 within 29 days of being treated. The trial looked at 1,062 hospitalized subjects with mild, moderate and severe COVID-19 who received Veklury (n=541) or placebo (n=521), plus standard of care. Recovery was defined as either being discharged from the hospital or being hospitalized but not requiring supplemental oxygen and no longer requiring ongoing medical care. The median time to recovery from COVID-19 was 10 days for the Veklury group compared to 15 days for the placebo group, a statistically significant difference."

    They did three clinical trials with remdesivir.
     
  5. Compassion

    Compassion Let's do business together. PRO VIP Gold Account ★★★★★★★★★★

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    COVID and the Medical System, Clinical Trials and News From WHO | Dr. Pam Popper

     
  6. koolishman

    koolishman Upgraded Member Blue Account

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    AstraZeneca’s Oxford COVID-19 vaccine provokes immune response

    AstraZeneca’s coronavirus vaccine accurately follows genetic instructions programmed into it by its developers at Oxford University — successfully provoking a powerful immune response, according to an analysis by independent scientists.

    “Until now, the technology hasn’t been able to provide answers with such clarity, but we now know the vaccine is doing everything we expected and that is only good news in our fight against the illness,” said David Matthews, a virology expert at Bristol University who led the research.
     
    Last edited: Oct 23, 2020
  7. Mister Funsky

    Mister Funsky Top Contributor VIP

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  8. J Sokol

    J Sokol Top Contributor VIP

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    The inevitable has happened in my workplace -- an employee tested positive for Covid. I say it was inevitable because 90% of the staff are Covid deniers, with few wearing masks or observing social distancing. We were all tested Thursday (Day 3) and so far everyone has tested negative.

    This got me to wondering how positive tests are reported. I think the official counts come from tallying results from each county in the country, but I'm curious whether all positive test results get added to the official totals.
     
  9. JB Lions

    JB Lions Top Contributor VIP ★★★★★★★★★★

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    I just noticed - https://www.worldometers.info/coronavirus/country/us/

    America just broke a record with 81,210 cases on 10/23. A new daily high.

    7 day average now 64,000+

    Sep 12th it was 35,000+

    Starting to shoot up like they said it would

    --------
    Wearing masks could save more than 100,000 US lives through February, new study suggests

    If 95% of Americans wore masks in public, more than 100,000 lives could be saved from Covid-19 through February, a new modeling study suggests.

    https://www.nature.com/articles/s41591-020-1132-9
     
    Last edited: Oct 24, 2020
  10. Cal2

    Cal2 Established Member

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  11. Mister Funsky

    Mister Funsky Top Contributor VIP

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    Current Covid19 death numbers as of 9:00 am EST are below, primarily from the source in the original post (https://www.worldometers.info/coronavirus). If your country of interest is not listed below, simply go to the link above to do a search for relevant information.

    Total: 1,150,769
    United States: 229,317
    Brazil: 156,528
    South Africa: 18,891
    United Kingdom: 44,571
    Canada: 9,888
    Mexico: 88,312
    Russia: 25,821
    India: 117,992
    Bolivia: 8,608
    Japan : 1,694
    Indonesia: 13,205
    Italy: 37,059
    Spain: 34,752
    Belgium: 10,658
    France: 34,508
    Netherlands: 6,964
    Chile: 13,844
    Philippines: 6,934
     
  12. J Sokol

    J Sokol Top Contributor VIP

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  13. Mister Funsky

    Mister Funsky Top Contributor VIP

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    Current Covid19 death numbers as of 10:00 am EST are below, primarily from the source in the original post (https://www.worldometers.info/coronavirus). If your country of interest is not listed below, simply go to the link above to do a search for relevant information.

    Total: 1,156,181
    United States: 230,086
    Brazil: 156,926
    South Africa: 18,944
    United Kingdom: 44,745
    Canada: 9,922
    Mexico: 88,743
    Russia: 26,050
    India: 118,619
    Bolivia: 8,627
    Japan : 1,706
    Indonesia: 13,299
    Italy: 37,210
    Spain: 34,752
    Belgium: 10,737
    France: 34,645
    Netherlands: 7,046
    Chile: 13,892
    Philippines: 6,977
     
    Last edited: Oct 25, 2020
  14. DmitrySV

    DmitrySV Established Member

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    https://agenciabrasil.ebc.com.br/saude/noticia/2020-10/marcos-pontes-fala-sobre-nitazoxanida

    The Minister of Science, Technology and Innovation (MCTI), Marcos Pontes, pointed out on Monday (19), in an interview with the program A Voz do Brasil , produced by the Empresa Brasil de Comunicação (EBC) , that the drug nitazoxanide has the capacity to reduce the viral load of covid-19 by 95% in patients at the beginning of treatment.

    “Nitazoxanide started to be tested in February, along with another 2,000 drugs initially with artificial intelligence, mathematical modeling, computer graphics at the National Biosciences Laboratory and, of these, in five of them they showed the ability to inhibit the virus, at least in simulated form. . There they were tested in vitro, in human cells and, of these five, nitazoxanide showed 95% reduction, inhibition of the virus ”, he explained. According to the minister, the research data will be released after review and publication in an international scientific journal.

    According to the minister, double-blind tests were performed, when neither the patient nor the doctor knows which medication is being taken, and randomized, when patients are randomly assigned to two groups, one receiving the medication and the other receiving a placebo. The offered dose was 500 milligrams of nitazoxanide, three times a day, or the placebo for five days.

    “Clinical tests were carried out with 1,500 patients and the tests showed that, in fact, this drug reduces viral load. That was the purpose of the test. [Reduces] viral load for patients admitted early, who were detected with covid-19, start treatment, ”he said.

    In making the research announcement, the minister said that the drug cannot be used by those who do not show symptoms of the disease, but only for people in the early stage of infection. "It is not prophylactic, it is not for prevention. It is only after the virus is detected," he said. Nitazoxanide is a vermifuge already known in Brazil, currently used in the treatment of rotavirus.

    According to Marcos Pontes, the inclusion of the drug in the treatment protocol for the new coronavirus in the Unified Health System (SUS) will be made after analysis by the Ministry of Health.
     
  15. CraigD

    CraigD Top Contributor VIP

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    Is something amiss with those US numbers? ;)
     
    Last edited: Oct 25, 2020
  16. Mister Funsky

    Mister Funsky Top Contributor VIP

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    Yep, it looks like the Brazil numbers were inserted...thanks for catching.
     
  17. koolishman

    koolishman Upgraded Member Blue Account

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    Vaccine hopes rise as Oxford jab prompts immune response among old as well as young adults

    One of the world’s leading COVID-19 experimental vaccines produces a immune response in both young and old adults, raising hopes of a path out of the gloom and economic destruction wrought by the novel coronavirus.
    The vaccine, developed by the University of Oxford, also triggers lower adverse responses among the elderly, British drug maker AstraZeneca Plc, which is helping manufacture the vaccine, said on Monday.


    “It is encouraging to see immunogenicity responses were similar between older and younger adults and that reactogenicity was lower in older adults, where the COVID-19 disease severity is higher,” an AstraZeneca spokesman said.
     
  18. Mister Funsky

    Mister Funsky Top Contributor VIP

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    Current Covid19 death numbers as of 9:00 am EST are below, primarily from the source in the original post (https://www.worldometers.info/coronavirus). If your country of interest is not listed below, simply go to the link above to do a search for relevant information.

    Total: 1,160,542
    United States: 230,510
    Brazil: 157,163
    South Africa: 18,968
    United Kingdom: 44,896
    Canada: 9,946
    Mexico: 88,924
    Russia: 26,269
    India: 119,057
    Bolivia: 8,645
    Japan : 1,711
    Indonesia: 13,411
    Italy: 37,338
    Spain: 34,752
    Belgium: 10,810
    France: 34,761
    Netherlands: 7,046
    Chile: 13,944
    Philippines: 7,039
     
  19. Mister Funsky

    Mister Funsky Top Contributor VIP

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  20. Sutruk

    Sutruk Top Contributor VIP

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    Very good news. That's the crucial point, to develop immune response also on older people:

    "The news that older people get an immune response from the vaccine is positive because the immune system weakens with age and older people are those most at risk of dying from the virus.

    If it works, a vaccine would allow the world to return to some measure of normality after the tumult of the pandemic."
     
  21. koolishman

    koolishman Upgraded Member Blue Account

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    People aware of the results from so-called immunogenicity blood tests carried out on a subset of older participants say the findings echo data released in July that showed the vaccine generated “robust immune responses” in a group of healthy adults aged between 18 and 55.

    What does this mean for 55+ and 18- ?
     
  22. Sutruk

    Sutruk Top Contributor VIP

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    That refers to the study from July, that was for people between 18 and 55.

    AstraZeneca says its vaccine trials suggest a promising immune response in older adults — the group at highest risk of COVID-19

    https://www.marketwatch.com/story/a...rials-offer-hope-for-older-adults-11603718356

    "The interim results further build on preliminary data from the Phase 1 and 2 clinical trials published in July in the medical journal The Lancet. The trial, which involved 1,077 healthy participants aged 18 to 55, showed that the vaccine induced two forms of human immune response generating antibodies and T-cells — for at least 56 days."

    On the last study, it was also for elder people:

    Oxford, AstraZeneca Vaccine Shows Promising Immune Response in Older Adults

    https://www.wsj.com/articles/oxford...g-immune-response-in-older-adults-11603713742

    The results showed positive outcomes for adults over 56, including the especially higher-risk age group of those 70 and older, and were based on analysis of previously conducted interim safety and immune-response data, AstraZeneca and Oxford said Monday.

    The elderly generally have been prone to more-severe Covid-19 symptoms than younger people. Thus, researchers have been looking for evidence that a vaccine will be able to specifically help protect them.
     
    Last edited: Oct 26, 2020
  23. J Sokol

    J Sokol Top Contributor VIP

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    You're Not Welcome Here: How Social Distancing Can Destroy The Global Economy

    Taking away the welcome mat is key to cutting off the path of the coronavirus. From the beginning of the pandemic, cities, states and countries have banned each other. And now, eight months into lockdowns that have led to immense stress and fatigue among people, some places around the world are introducing even more draconian measures.

    The path toward recovery continues to be inherently antisocial and runs counter to how humans interact, live lives and conduct their business. This unwelcome policy — which has already harmed families, societies and economies — has the potential to lead to a tectonic shift in how the world functions in the foreseeable future.


    https://www.npr.org/2020/10/26/9270...ial-distancing-can-destroy-the-global-economy
     
  24. J Sokol

    J Sokol Top Contributor VIP

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    They Work In Several Nursing Homes To Eke Out A Living, And That May Spread The Virus

    The UCLA study also found that some areas of the country have a much higher overlap in nursing home staffing than others.

    "There are some facilities in Florida, in New Jersey, where they're sharing upwards of 50 to 100 workers," says UCLA associate professor Elisa Long, who, along with her colleagues, examined data during the federal visitor ban from March to May. "This is over an 11-week time period, but that's a huge number of individuals that are moving between these facilities; all of these are potential sources of COVID transmission."

    They also found the more shared workers a nursing home has, the more COVID-19 infections among the residents.


    https://www.npr.org/sections/health...to-eke-out-a-living-and-that-spreads-the-viru
     
  25. J Sokol

    J Sokol Top Contributor VIP

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    It’s Time to Talk About Covid-19 and Surfaces Again

    Consider, Wyllie says, the extraordinary chain of events that would need to happen to successfully spread SARS-CoV-2 on a surface. A sufficiently large amount of the virus would need to be sprayed by an infected person onto a surface. The surface would need to be the right kind of material, exposed to the right levels of light, temperature, and humidity so that the virus does not quickly degrade. Then the virus would need to be picked up—which you would most likely do with your hands. But the virus is vulnerable there. (“Enveloped” viruses like SARS-CoV-2 do not fare well on porous surfaces like skin and clothing.) And then it needs to find a way inside you—usually through your nose or your eye—in a concentration big enough to get past your mucosal defenses and establish itself in your cells. The risk, Wyllie concludes, is low. “I’ve not once washed my groceries or disinfected my bags or even thought twice about my mail,” she says.

    Low risk is not, of course, no risk, she adds. There are high-touch objects that merit disinfection, and places like hospitals need clean rooms and furniture. People at high risk from Covid-19 may want to take extra precautions. But the best advice for breaking that object-to-nose chain, according to all the health experts I spoke with: Wash your hands.


    https://www.wired.com/story/its-tim...1ea302-9542-4825-bfde-27cf09c29c2f_popular4-1
     

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