Hi
MFA - made for adsense. Just how this is explained is subjective to who you ask. I would dub a MFA website as one that has little to no original content - usually articles from article directories, or the use of scraped content. Scraped content can be news feeds, blog posts from other blogs, or even right ripped off content from higher ranking websites. This scraped content is usually used in place of real content.
The drawbacks to MFA include but are not limited to - poor search results on the search engines because of the lack of real content and or duplicate content penalties, very poor user satisfaction, and little likelihood of someone naturally linking to your MFA or bookmarking it. Google has also seen fit to remove the worst of these from their search results. Obviously they haven't gotten them all, and may never, but if you value your domain name why risk having it dropped from the search index with no guarantee it will ever be re-included?
As for the rudimentary website I mentioned - I always use original text content - even if it is only a few hundred words per page. That one in particular was put up on a very ugly and plain template as a placeholder till I could finish the content/website at a later time. The advantage there is I can get it indexed by the search engines while finishing up the website. Just be sure if you copy that model that you take care to make that first page worth indexing - ie - proper keyword density, great title tag, and enough on-topic content that the search engines take notice of it.
Why would I use such an ugly template up front? Because of the way it is designed. It contains no javascript or other types of coding to trip up or otherwise turnaway the search crawlers, and it places my most important text - the original text copy - before the rest of the html code, so the crawlers are sure to find it as I intended them too.
Then there is the matter of actual ad unit layouts. I prefer the less is more approach when making minisites - or full blown websites for that matter. Just because you can use four adsense units per page doesn't mean you should every time. Let's face it - nobody likes seeing a webpage with more ads than text copy. It turns people away, and if they are not reading your website - they are not likely to click your ads, link to it, bookmark it, tell others about it etc etc etc.
Hope that helps.