For sure, the beauty of the site is that YOU are in control.
For instance, if you are an adsense or Yahoo Publisher e.g. YOU can set the keyword that will generate not only the relevant news and the overture suggestions on your mini site but also the relevant ads.
So, for your sites, you might set the keyword/s for "drinkingden.com" as 'alcohol' or 'drinking' or 'pubs' or 'UK pubs' - the choice is yours. Only you really know what your sites really is all about... There is no limit.
heres an example of what it might look like using "pubs" as the keyword :
http://www.1plus.net/?news=DrinkingDen.com&term=pubs
You can play around with different examples using the same format as the above url to get to where you wanna be...
Alternatively, you might set the keyword for 'drinkingden.com' as something completely unrelated - Again, the choice is yours.
Furthermore, if you dont want to / cant use adsense etc you may use ANY ads you want... If you have a CJ.com account, you can with their SmartZone feature create a single code and rotate multi ads on your pages, as detailed above,
www.1plus.net/YourDomain.com/ shows how this works.. refresh the page to see a different set of ads...
Hope that answers your question..